6533b858fe1ef96bd12b6e0d
RESEARCH PRODUCT
Energy compensation and adiposity in humans
Jacob Plange-rhuleHiroyuki SagayamaYosuke YamadaLara R. DugasLara R. DugasEllen E. BlaakCornelia U LoechlSumei HuStephane BlancStephane BlancSai Krupa DasJohn J. ReillySamuel S. UrlacherIssad BaddouRoss L. PrenticeKirsi H. PietiläinenBrian M. WoodBrian M. WoodGuy PlasquiKweku Bedu-addoWilliam E. KrausAsmaa El HamdouchiNancy F. ButteCatherine HamblyRoberto A RabinovichDale A. SchoellerErwin P. MeijerJames C MorehenJames C MorehenVincent CareauNoorjehan JoonasMarije B. HoosPhilip N. AinslieJennifer RoodTerrence ForresterJames P. MortonSimon EatonAlberto G. BonomiWilliam W. WongWilliam R. LeonardGraeme L. CloseJonathan C. K. WellsLene Frost AndersenRobert OjiamboAnnelies H. C. GorisBarry W. FudgeLewis G. HalseyPeter T. KatzmarzykLenore ArabMisaka KimuraGeorge S. WilsonRobert F. KushnerXueying ZhangXueying ZhangAlbertine J. SchuitSusan B. RacetteKitty P. KempenGiulio ValentiAmy LukeNader LessanUlf EkelundAnnemiek M. C. P. JoosenAnders SjödinSusan B. RobertsAnine Christine MedinAnine Christine MedinMarian L. NeuhouserEric RavussinMaciej S. BuchowskiYannis P. PitsiladisMichael GurvenDavid A. RaichlenEdgar A. Van MilJack A. YanovskiLiam J. AndersonTsukasa YoshidaCorby K. MartinJamie A. CooperStefan G J A CampsJohn R. SpeakmanRichard CooperRebecca M. ReynoldsAlexia J. Murphy-alfordLudo M. Van EttenCarlijn V. C. BoutenEstelle V. LambertEric SticeTheresa A. NicklasHerman PontzerSonja EntringerSonja Entringersubject
Calorie030309 nutrition & dieteticsEnergy balanceRA773SDG 3 – Goede gezondheid en welzijnCardiovascularMedical and Health SciencesOral and gastrointestinalCompensation (engineering)RC12000302 clinical medicineWeight lossenergy compensationAdiposityCancer0303 health sciencesexerciseCONSTRAINTBiological SciencesStrokeIAEA DLW database groupEXERCISE PHYSICAL-ACTIVITYmedicine.symptomGeneral Agricultural and Biological SciencesINTERVENTIONSEnergy (esotericism)WEIGHT-LOSS030209 endocrinology & metabolismMASSBiologyArticleGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesAffordable and Clean EnergySDG 3 - Good Health and Well-beingTotal energy expenditureClinical Researchdaily energy expendituremedicineVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470HumansBASALObesityMetabolic and endocrineenergy management modelsNutritionHomo sapiensBIRDSactivityPsychology and Cognitive Sciencesmedicine.diseaseObesitytrade-offsMETABOLIC-RATESBasal metabolic ratebasal metabolic rate1182 Biochemistry cell and molecular biologyDemographic economics3111 Biomedicineweight lossEnergy MetabolismEnergy IntakeEXPENDITUREDevelopmental Biologydescription
Publisher Copyright: © 2021 The Authors Understanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures.1–3 This suggestion has profound implications for both the evolution of metabolism and human health. It implies that a long-term increase in activity does not directly translate into an increase in total energy expenditure (TEE) because other components of TEE may decrease in response—energy compensation. We used the largest dataset compiled on adult TEE and basal energy expenditure (BEE) (n = 1,754) of people living normal lives to find that energy compensation by a typical human averages 28% due to reduced BEE; this suggests that only 72% of the extra calories we burn from additional activity translates into extra calories burned that day. Moreover, the degree of energy compensation varied considerably between people of different body compositions. This association between compensation and adiposity could be due to among-individual differences in compensation: people who compensate more may be more likely to accumulate body fat. Alternatively, the process might occur within individuals: as we get fatter, our body might compensate more strongly for the calories burned during activity, making losing fat progressively more difficult. Determining the causality of the relationship between energy compensation and adiposity will be key to improving public health strategies regarding obesity. Peer reviewed
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-10-25 |