6533b859fe1ef96bd12b79ba
RESEARCH PRODUCT
COVID-19 infection and glucocorticoids: update from the Italian Society of Endocrinology Expert Opinion on steroid replacement in adrenal insufficiency
Marco BoscaroCarla GiordanoEmilia SbardellaAlberto FalorniAndrea M. IsidoriCarla ScaroniGiorgio ArnaldiMary Anna VenneriAndrea LenziChiara SimeoliRosario PivonelloRiccardo PofiRoberta GiordanoValeria Hasenmajersubject
medicine.medical_specialty2019-20 coronavirus outbreakConsensusCoronavirus disease 2019 (COVID-19)Hormone Replacement TherapyEndocrinology Diabetes and MetabolismSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralConsensuEndocrinologyGlucocorticoidmedicineAdrenal insufficiencyHumansSteroids.Hormone replacement therapyViralIntensive care medicinePandemicsAdrenal insufficiency; COVID-19; Glucocorticoids; SARS-CoV2GlucocorticoidsPandemicbusiness.industryCoronavirus InfectionCOVID-19Pneumoniamedicine.diseaseCOVID-19 Drug TreatmentItalyExpert opinionSARS-CoV2SteroidsbusinessCoronavirus InfectionsCoronavirus InfectionsAdrenal insufficiencyHumandescription
In November 2019, the Italian Society of Endocrinology (SIE) has published a consensus statement on the tailoring of glucocorticoid replacement in adrenal insufciency [1]. A few months later, a novel severe acute respiratory syndrome coronavirus (SARS-CoV2) has been recognized as responsible for COVID-19. The outbreak has now reached pandemic level, with a high global mortality rate [2]. From February on, Italy has experienced an exponential rise in the infected which is estimated to reach 200,000 people, with an overall lethality of approximately 10% [3]. A recent Chinese series of nearly 50,000 patients with confrmed COVID-19 infection found that approximately one-out-of-fve (19%) evolve towards severe (14%) or critical (5%) pneumonia [4]. Several clinical trials are now testing the therapeutic options to treat lung and extra-respiratory complications of SARSCoV2 infection. While awaiting for a specifc treatment strategy, the SIE task force met again to address the tailoring of corticosteroid replacement in adrenal insufcient patients coping with the stress related to COVID-19 infection
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-04-25 |