6533b859fe1ef96bd12b79c3

RESEARCH PRODUCT

TYPE II DIABETES MELLITUS HAS NO MAJOR INFLUENCE ON PLATELET MICRO–RNA EXPRESSION: RESULTS FROM MICRO–ARRAY PROFILING IN A COHORT OF 60 PATIENTS

Michael AmannThomas G. NuehrenbergBernd L. FiebichHarald BinderFranz J NeumannWillibald HochholzerDietmar TrenkChristian Stratz

subject

business.industryInflammationMicro arraymedicine.diseaseType ii diabetesDiabetes mellitusCohortmicroRNAImmunologymedicinePlateletmedicine.symptomCardiology and Cardiovascular Medicinebusiness

description

Blood platelets represent pro–inflammatory mediators in the development of atherosclerosis. Diabetes mellitus as a major contributor to cardiovascular disease burden induces dysfunctional platelets. Platelets contain abundant miRNAs, which recently have been linked tightly to inflammation. While

10.1016/s0735-1097(13)62036-7http://dx.doi.org/10.1016/S0735-1097(13)62036-7