6533b859fe1ef96bd12b817c
RESEARCH PRODUCT
Molecular characterization of Italian Candida parapsilosis isolates reveals the cryptic presence of the newly described species Candida orthopsilosis in blood cultures from newborns
Orazio RomeoGiuseppe CriseoAntonio CascioBarbara CostanzoDemetrio Delfinosubject
Microbiology (medical)Species complexSettore MED/07 - Microbiologia E Microbiologia ClinicaCandida parapsilosisSettore MED/17 - Malattie InfettiveMolecular Sequence DataBiologyCandida parapsilosisAlcohol OxidoreductaseMicrobiologyCandida orthopsilosisCandida orthopsilosiCANDIDA ORTHOPSILOSISDNA Ribosomal SpacerHumansSensu strictoNewbornsCandidaITS-sequencingCross InfectionNosocomial pathogensCandidiasisInfant NewbornCandida metapsilosisGeneral Medicinebiology.organism_classificationNewbornVenous.centralAlcohol OxidoreductasesCandida metapsilosiInfectious DiseasesItalyMolecular epidemiologyCandida parapsilosis Candida orthopsilosis Candida metapsilosis Molecular epidemiology SADH gene ITS-sequencing NewbornsCandidiasiCandida parapsilosiFemaleSADH geneHumandescription
The authors report the molecular characterization of Candida parapsilosis isolates recovered from the blood and venous central catheter tips of patients admitted to different care units of the Polyclinic Hospital, University of Messina, Italy. Among 97 presumed C. parapsilosis isolates examined, 94 were identified as C. parapsilosis sensu stricto and the remaining 3 isolates were found to belong to the cryptic species Candida orthopsilosis which was recovered only from blood cultures of neonates (<30 days old) born prematurely. No C. metapsilosis was found in this study. This study emphasizes the role of C. parapsilosis as an important nosocomial pathogen, and it also describes, for the first time, the occurrence of C. orthopsilosis in newborns. © 2012 Elsevier Inc..
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-01-01 |