6533b859fe1ef96bd12b8314

RESEARCH PRODUCT

Solitary fibrous tumor of the floor of the mouth

Danielle Resende CamisascaAethel Gladys De Oliveira FernandesAndré Aguiar MarquesSimone De Queiroz Chaves LourençoRenata Miranda RodriguesSilvia Paula De Oliveira

subject

Solitary fibrous tumorPathologymedicine.medical_specialtyOral Medicine and PathologyFloor of mouthbiologymedicine.diagnostic_testbusiness.industryCD34Case ReportVimentinAnatomymedicine.disease:CIENCIAS MÉDICAS [UNESCO]UNESCO::CIENCIAS MÉDICASEosinophilicBiopsybiology.proteinmedicineDifferential diagnosisbusinessGeneral DentistryEpithelioid cell

description

Background A solitary fibrous tumor (SFT) of the oral cavity is an extremely rare entity. Its diagnosis is complicated because of its diverse morphology and similarity to other mesenchymal diseases. Case Report A rare case of SFT involving floor of the mouth is presented. The tumor was well circumscribed and almost spherical, measuring approximately 3 cm in diameter. Patient was submitted to biopsy and histopathologic examination showed a tumor composed of spindle to epithelioid cells showing pale to eosinophilic cytoplasm, oval or elongated nuclei with inconspicuous nucleoli. Tumor cells showed strong positivity for CD34, vimentin and Bcl-2. SFTs may present as a diagnostic challenge. The patient was followed for 8 years without recurrences. Results SFT is an uncommon disease in maxillofacial region; however it should be considered in the differential diagnosis of spindle cell neoplasms with oral manifestation. Only a few cases have been reported in the floor of mouth. We describe a new case of SFT arising at this location. Key words:Solitary fibrous tumors, mouth floor, oral diagnosis.

yearjournalcountryeditionlanguage
2017-09-01
http://hdl.handle.net/10550/63377