Synthesis of novel functionalized cispentacins through C–C oxidative cleavage of diendo-norbornene β-amino acid

6533b859fe1ef96bd12b8402

RESEARCH PRODUCT

Synthesis of novel functionalized cispentacins through C–C oxidative cleavage of diendo-norbornene β-amino acid

Maria Cherepanova Reijo Sillanpää Loránd Kiss Ferenc Fülöp Ferenc Fülöp

subject

chemistry.chemical_classification Double bond Stereochemistry General Chemical Engineering General Chemistry Oxidative phosphorylation Cleavage (embryo)Amino acid Stereocenter chemistry.chemical_compound chemistry Dihydroxylation Wittig reaction ta116 Norbornene

description

Difunctionalized cispentacin derivatives with two new stereogenic centres have been synthesized from a diendo-norbornene β-amino acid in a stereocontrolled route, involving C–C double bond functionalization by dihydroxylation, followed by oxidative ring cleavage and transformation of the dialdehyde intermediates through a Wittig reaction.

year	journal	country	edition	language
2013-01-01	RSC Advances

https://doi.org/10.1039/c3ra41963k

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