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RESEARCH PRODUCT
Vitamin D Deficiency in HIV Infection: Not Only a Bone Disorder
Antonio CascioGiustina VitaleChiara IariaSebastiano GangemiPasquale MansuetoAurelio Seiditasubject
Settore MED/09 - Medicina InternaBone diseasePopulationlcsh:MedicineHIV InfectionsReview ArticleDiseaseGeneral Biochemistry Genetics and Molecular Biologyvitamin D deficiencyRisk FactorsAntiretroviral Therapy Highly ActivePrevalenceVitamin D and neurologyHumansMedicineHIV InfectionAntiretroviral Therapy Highly Active; HIV Infections; Humans; Prevalence; Risk Factors; Vitamin D Deficiency; Bone Diseases; Biochemistry Genetics and Molecular Biology (all); Immunology and Microbiology (all)educationeducation.field_of_studyType 1 diabetesGeneral Immunology and Microbiologybusiness.industryRisk Factorlcsh:RType 2 Diabetes MellitusVitamin D Deficiency; HIV Infection; Bone DisorderGeneral MedicineVitamin D Deficiencymedicine.diseaseImmunologyBone DiseasesMetabolic syndromebusinessHumandescription
Hypovitaminosis D is a worldwide disorder, with a high prevalence in the general population of both Western and developing countries. In HIV patients, several studies have linked vitamin D status with bone disease, neurocognitive impairment, depression, cardiovascular disease, high blood pressure, metabolic syndrome, type 2 diabetes mellitus, infections, autoimmune diseases like type 1 diabetes mellitus, and cancer. In this review, we focus on the most recent epidemiological and experimental data dealing with the relationship between vitamin D deficiency and HIV infection. We analysed the extent of the problem, pathogenic mechanisms, clinical implications, and potential benefits of vitamin D supplementation in HIV-infected subjects.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-04-01 | BioMed Research International |