6533b85bfe1ef96bd12baad4

RESEARCH PRODUCT

Chemistry and biology of new marine alkaloids from the indole and annelated indole series.

Alparslan AygünUlf Pindur

subject

PharmacologyIndole testIndolesChemistryOrganic ChemistryAntineoplastic AgentsMarine BiologyMarine Biology (journal)BiochemistryChemical synthesisBiological FactorsStructure-Activity RelationshipAlkaloidsAnti-Infective AgentsPharmaceutical PreparationsDrug DiscoveryMolecular MedicineOrganic chemistryAnimalsBiological evaluation

description

Chemistry and biology of marine natural products from the indole and annelated indole series have become an attractive research field for development of new pharmacological lead substances. In the past years some of the isolated natural organic compounds were synthesized by chemists and evaluated with great enthusiasm to find new lead natural compounds against different diseases. In this review the latest results for new compounds including isolation, biological evaluation, synthetic pathways and some retrosynthetic analyses are summarized.

10.2174/0929867033457511https://pubmed.ncbi.nlm.nih.gov/12678805