6533b85bfe1ef96bd12bab42

RESEARCH PRODUCT

Electronic buccal drug delivery system to treat addiction and chronic diseases: A porcine study in the frame of “IntelliDrug” project

subject

description

examination followed by the administration of a risk factor questionnaire. A cervical, buccal, occlusal/incisal, and lingual score was recorded for each tooth using a modified version of the Tooth Wear Index (Smith and Knight, 1984). Rank correlations, one-way and two-way ANOVA were used to test for associations between risk factors and percent of surfaces with wear. Results: 44 patients (31.9%) had at least one cervical lesion 1-2mm deep. 118 patients (85%) had dentin exposure on at least one incisal edge. Cervical lesions were most frequently observed on mandibular 1 premolars. Incisal/occlusal wear was most common on mandibular central incisors. Age was significantly correlated with overall wear (r 0.53, P 0.01). Two-way ANOVA indicated an interaction between age and GERD, and separate one-way ANOVAs by age groups showed that, among patients under 44 years of age, those with symptoms of GERD had significantly more wear than those without any symptoms of GERD (P 0.02). No other risk factors were associated with wear. Conclusions: Our data indicate the most prevalent sites of non-carious tooth wear and the frequency of pathological lesions. Age and GERD were shown to be significant risk factors for tooth wear. Future epidemiologic risk factor studies should examine purported risk factors in homogenous age groups. Supported by: NIH/NIDCR T32DE07023.