6533b85bfe1ef96bd12bad5b
RESEARCH PRODUCT
Retinal detachment with spontaneous dialysis of the ora serrata in a 13-year-old child with neurofibromatosis type 1: a case report.
Noemí Ruiz Del RíoA. Gargallo-benedictoJosé M Hervas-hernándisR. Clemente-tomásAntonio Duch-samperFrancisca García-iborsubject
Pars planamedicine.medical_specialtygenetic structuresmedicine.medical_treatmentCase Reportsneurofibromatosis type 1Avulsion03 medical and health sciences0302 clinical medicinelcsh:OphthalmologyOphthalmologyfibroblastsmedicineOra serrataNeurofibromatosisDialysisRetinabusiness.industryrhegmatogenous retinal detachmentRetinal detachmentdialysis of the ora serratamedicine.diseaseeye diseasesvitreous baseOphthalmologymedicine.anatomical_structurelcsh:RE1-994030221 ophthalmology & optometrysense organsbusinessVitreous baseUlls030217 neurology & neurosurgerydescription
A 13‑year‑old child diagnosed with neurofibromatosis type 1 who on a routine control presented with rhegmatogenous retinal detachment associated to dialysis of the ora serrata in the left eye (OS). There were no clinical signs or history of contuse ocular trauma. Neurofibromatosis produces alterations in fibroblasts of the cortex of the vitreous base. This results in deficient production of the collagen fibers that anchor the vitreous base to the pars plana and the peripheral neurosensory retina. Thus, suboptimal function of the fibroblasts explains spontaneous avulsion of the vitreous base. Such avulsion in turn is related to dialysis of the ora serrata.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-06-01 |