6533b85bfe1ef96bd12bad5c

RESEARCH PRODUCT

Executive summary of the 2018 KDIGO Hepatitis C in CKD Guideline: welcoming advances in evaluation and management

Vivekanand JhaVivekanand JhaNassim KamarNassim KamarJosé M. MoralesChing-lung LaiCraig E. GordonJacques IzopetStanislas PolMengyang DiPaul J. MartinMarcelo SilvaAmy EarleyWahid DossBertram L. KasiskeMichel JadoulEthan M BalkFabrizio FabriziPriti R. PatelMarina Berenguer

subject

Liver Cirrhosishepatitis C virusmedicine.medical_treatment030232 urology & nephrologylcsh:RC870-923medicine.disease_causecryoglobulinemialiver testingantivirals0302 clinical medicinesystematic reviewMedicineInfection controlKidney transplantationKDIGOCross Infectionhemodialysisnosocomial transmissionvirus diseasesHepatitis CHepatitis Cinfection controlNephrologyPractice Guidelines as Topic030211 gastroenterology & hepatologyHemodialysisguidelineGlomerular Filtration Ratemedicine.medical_specialtyHepatitis C viruskidney transplantationAntiviral Agents03 medical and health sciencesRenal DialysisDisease Transmission InfectiousHumansRenal Insufficiency ChronicIntensive care medicineglomerular diseasesdirect-acting antiviralsDialysisbusiness.industryscreeningGuidelinelcsh:Diseases of the genitourinary system. Urologymedicine.diseaseKidney Transplantationdialysisbusinesschronic kidney diseaseKidney disease

description

Infection with the hepatitis C virus (HCV) has adverse liver, kidney, and cardiovascular consequences in patients with chronic kidney disease (CKD), including those on dialysis therapy and in those with a kidney transplant. Since the publication of the original Kidney Disease: Improving Global Outcomes (KDIGO) HCV Guideline in 2008, major advances in HCV management, particularly with the advent of direct-acting antiviral therapies, have now made the cure of HCV possible in CKD patients. In addition, diagnostic techniques have evolved to enable the noninvasive diagnosis of liver fibrosis. Therefore, the Work Group undertook a comprehensive review and update of the KDIGO HCV in CKD Guideline. This Executive Summary highlights key aspects of the guideline recommendations.

https://doi.org/10.1016/j.kint.2018.06.011