6533b85bfe1ef96bd12bb50a

RESEARCH PRODUCT

Ischemia in patients with no obstructive coronary artery disease: classification, diagnosis and treatment of coronary microvascular dysfunction

Alfredo R. GalassiNicola CaronnaVincenzo SucatoMirko LuparelliMarianna RubinoSalvatore EvolaSalvatore NovoGiuseppina NovoAntonino SaladinoAlessandro D'agostino

subject

medicine.medical_specialtyPopulationIschemiavasospastic angina030204 cardiovascular system & hematologyCoronary AngiographyPoor qualityCoronary artery disease03 medical and health sciences0302 clinical medicineCoronary CirculationInternal medicinemedicineHumansIn patient030212 general & internal medicineAngina symptomseducationeducation.field_of_studyVasospastic anginacoronary microvascular dysfunctionbusiness.industryMicrocirculationTakotsubo SyndromeDisease ManagementGeneral Medicinemedicine.diseaseCoronary Vesselsmyocardial ischemiaCoronary Occlusionmicrovascular anginaQuality of LifeCardiologyCardiology and Cardiovascular Medicinebusiness

description

Patients with coronary microvascular dysfunction represent a widespread population, and despite the good prognosis, many of them, because of the angina symptoms, have a poor quality of life with strong limitations in their daily activities. In 2017, a new classification of microvascular dysfunction as well as a new definition of ischemia in patients with no obstructive coronary artery disease became available. This new definition improves Kemp's initial work, where cardiac X syndrome was initially described. This work summarizes the last updates on the subject with particular attention to the new classification of microvascular dysfunction, with particular attention to microvascular and vasospastic angina definition and diagnostic criteria.

https://doi.org/10.1097/mca.0000000000000855