0000000001034276

AUTHOR

Antonino Saladino

0000-0001-9535-5039

showing 4 related works from this author

Reverse remodeling and arrhythmic burden reduction in a patient with an implantable cardioverter defibrillator treated with sacubitril/valsartan: Cas…

2020

Abstract Sacubitril/valsartan has been shown to reduce cardiovascular mortality and hospitalizations in patients with HFrEF when compared to enalapril. There are also some evidences of its potential antiarrhythmic effects. We present a report where we found a relation between reverse ventricular remodeling and arrhythmic reduction in a patient treated with sacubitril/valsartan.

medicine.medical_specialtymedicine.medical_treatmentARNIlcsh:Medicineheart failureCase ReportheartCase Reports030204 cardiovascular system & hematologySacubitril03 medical and health sciences0302 clinical medicineInternal medicinemedicineEnalaprilVentricular remodelingReverse remodelingarrhythmic burdenremodelinglcsh:R5-920business.industrylcsh:RGeneral Medicinemedicine.diseaseImplantable cardioverter-defibrillatorfailureValsartan030220 oncology & carcinogenesisHeart failureCardiologylcsh:Medicine (General)businessSacubitril Valsartanmedicine.drugClinical Case Reports
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Correlation between longitudinal strain analysis and coronary microvascular dysfunction in patients with heart failure with preserved ejection fracti…

2020

Objective: The aim of this study was to evaluate in patients with microvascular angina and heart failure with preserved ejection fraction, the speckle-tracking echocardiography, and longitudinal myocardial strain to evaluate the possible presence of alterations in heart failure with preserved ejection fraction patients compared with a control population. We also investigated the correlation between the longitudinal strain analysis and the TIMI frame count after coronary angiography. Methods: Our study was performed on a population 41 patients with microvascular angina that underwent coronary angiography and speckle-tracking echocardiography. We divided the sample into two categories: patien…

Malemedicine.medical_specialtyLongitudinal strainPhysiologyPopulation030204 cardiovascular system & hematologyMicrocirculationCorrelation03 medical and health sciences0302 clinical medicineTIMI frame countPhysiology (medical)Internal medicineCoronary CirculationmedicineHumansIn patienteducationMolecular BiologySubclinical infectionAgedHeart Failureeducation.field_of_studycoronary microvascular dysfunctionbusiness.industryMicrocirculationStroke VolumeMiddle AgedHeart failure with preserved ejection fractionEchocardiographyCardiologyFemaleCardiology and Cardiovascular MedicinebusinessHeart failure with preserved ejection fraction030217 neurology & neurosurgeryTIMIglobal longitudinal strain
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Ischemia in patients with no obstructive coronary artery disease: classification, diagnosis and treatment of coronary microvascular dysfunction

2020

Patients with coronary microvascular dysfunction represent a widespread population, and despite the good prognosis, many of them, because of the angina symptoms, have a poor quality of life with strong limitations in their daily activities. In 2017, a new classification of microvascular dysfunction as well as a new definition of ischemia in patients with no obstructive coronary artery disease became available. This new definition improves Kemp's initial work, where cardiac X syndrome was initially described. This work summarizes the last updates on the subject with particular attention to the new classification of microvascular dysfunction, with particular attention to microvascular and vas…

medicine.medical_specialtyPopulationIschemiavasospastic angina030204 cardiovascular system & hematologyCoronary AngiographyPoor qualityCoronary artery disease03 medical and health sciences0302 clinical medicineCoronary CirculationInternal medicinemedicineHumansIn patient030212 general & internal medicineAngina symptomseducationeducation.field_of_studyVasospastic anginacoronary microvascular dysfunctionbusiness.industryMicrocirculationTakotsubo SyndromeDisease ManagementGeneral Medicinemedicine.diseaseCoronary Vesselsmyocardial ischemiaCoronary Occlusionmicrovascular anginaQuality of LifeCardiologyCardiology and Cardiovascular MedicinebusinessCoronary Artery Disease
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Coronary microvascular dysfunction

2020

Patients with coronary microvascular dysfunction (CMVD) represent a widespread population and despite the good prognosis, many of them have a poor quality of life with strong limitations in their daily activities because of the angina symptoms. This article summarizes the most frequent clinical presentation pictures like stable and unstable microvascular angina. Main risk factors are discussed, followed by the latest updates on the subject about different pathogenic hypotheses, diagnosis and treatment. Not very well understood microvascular alterations, like slow flow phenomenon and no reflow are discussed and both prognosis and the impact of the disease in the quality of life are analyzed.

medicine.medical_specialtyMyocardial ischemiaMyocardial ischemiaPopulationDisease030204 cardiovascular system & hematologyPoor quality03 medical and health sciences0302 clinical medicineMicrovascular anginaRisk FactorsCoronary CirculationInternal medicineHumansMedicine030212 general & internal medicineAngina symptomseducationeducation.field_of_studybusiness.industryMicrovascular anginaSlow-Flow PhenomenonPrognosisCoronary VesselsHearth failureQuality of LifeCardiologyNo-Reflow PhenomenonCardiology and Cardiovascular Medicinebusiness
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