6533b86cfe1ef96bd12c8bc9

RESEARCH PRODUCT

Coronary microvascular dysfunction

Antonino SaladinoAlfredo R. GalassiSalvatore EvolaVincenzo SucatoGiuseppina Novo

subject

medicine.medical_specialtyMyocardial ischemiaMyocardial ischemiaPopulationDisease030204 cardiovascular system & hematologyPoor quality03 medical and health sciences0302 clinical medicineMicrovascular anginaRisk FactorsCoronary CirculationInternal medicineHumansMedicine030212 general & internal medicineAngina symptomseducationeducation.field_of_studybusiness.industryMicrovascular anginaSlow-Flow PhenomenonPrognosisCoronary VesselsHearth failureQuality of LifeCardiologyNo-Reflow PhenomenonCardiology and Cardiovascular Medicinebusiness

description

Patients with coronary microvascular dysfunction (CMVD) represent a widespread population and despite the good prognosis, many of them have a poor quality of life with strong limitations in their daily activities because of the angina symptoms. This article summarizes the most frequent clinical presentation pictures like stable and unstable microvascular angina. Main risk factors are discussed, followed by the latest updates on the subject about different pathogenic hypotheses, diagnosis and treatment. Not very well understood microvascular alterations, like slow flow phenomenon and no reflow are discussed and both prognosis and the impact of the disease in the quality of life are analyzed.

10.23736/s0026-4725.20.05070-7http://hdl.handle.net/10447/439066