6533b85bfe1ef96bd12bb56d

RESEARCH PRODUCT

Platelet-Rich Plasma (PRP) in Dental Extraction of Patients at Risk of Bisphosphonate-Related Osteonecrosis of the Jaws: A Two-Year Longitudinal Study

Vera PanzarellaGiuseppe PizzoGabriele CervinoOlga Di FedeGiacomo OteriGiuseppina CampisiGiuseppina MazzolaRodolfo Mauceri

subject

Longitudinal studymedicine.medical_specialtybisphosphonatePRPmedicine.medical_treatmentONJosteonecrosis of the jawslcsh:TechnologyMetabolic bone diseaselcsh:Chemistry03 medical and health sciences0302 clinical medicineSettore MED/28 - Malattie OdontostomatologicheInternal medicinemedicineGeneral Materials ScienceAutologous plateletProspective cohort studyInstrumentationbisphosphonateslcsh:QH301-705.5Fluid Flow and Transfer Processesbusiness.industrylcsh:TProcess Chemistry and TechnologyGeneral EngineeringCancerplatelet-rich plasma030206 dentistryBisphosphonatemedicine.diseaselcsh:QC1-999Computer Science Applicationsosteonecrosis of the jawDental extractionlcsh:Biology (General)lcsh:QD1-999lcsh:TA1-2040030220 oncology & carcinogenesisPlatelet-rich plasmadental extractionbusinesslcsh:Engineering (General). Civil engineering (General)lcsh:Physics

description

: Dental extraction has often been described as the main trigger event of osteonecrosis of the jaws (ONJ). This longitudinal hospital-based study aimed to evaluate the outcome at 2 years of a standardized medical-surgical protocol for dental extraction, combined with platelet rich-plasma (PRP) application, compared with conventional protocol not combined with PRP or any other autologous platelet concentrate in cancer (ONC) and osteometabolic (OST) patients, at risk of bisphosphonate (BP)-related ONJ. Twenty patients were consecutively recruited: six received BPs for cancer skeletal-related events (34.17 &plusmn

yearjournalcountryeditionlanguage
2020-06-29Applied Sciences
10.3390/app10134487https://www.mdpi.com/2076-3417/10/13/4487