6533b85cfe1ef96bd12bc7e5

RESEARCH PRODUCT

Radioimmunoassay of Plasma and Urinary Norepinephrine

U. KrauseK. PollowB. ManzJ. BeyerM. Lorey

subject

Norepinephrine (medication)chemistry.chemical_compoundChromatographyPlasma norepinephrineChemistryUrinary systemmedicineRadioimmunoassayNormetanephrinemedicine.drug

description

Various analytical methods, such as fluorimetry, radioenzymic assay and in particular liquid chromatography are used for the analysis of norepinephrine (NA) in body fluids and tissue homogenates. These procedures, however, often lack sensitivity, are expensive and/or time consuming. Basing on our previous reports on the radioimmunoassay of chemically modified serotonin1, 5-hydroxy-3-indole acetic acid2 and normetanephrine (NMN)3, a sensitive radioimmunoassay of the N-acetyl,3-methoxy analogue of urinary and plasma norepinephrine was developed.

https://doi.org/10.1007/978-3-642-83858-3_62