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RESEARCH PRODUCT
Pharmacogenomics in psychiatry: from therapeutic drug monitoring to genomic medicine.
Christoph HiemkeSéverine CrettolChin B. EapJ. De Leonsubject
medicine.medical_specialtyGenotypeAlternative medicineNicePharmacotherapyNeed to knowmedicineGenomic medicineAnimalsHumansPharmacology (medical)Precision MedicinePsychiatrycomputer.programming_languagePharmacologyPsychiatryPsychotropic Drugsmedicine.diagnostic_testbusiness.industryMental DisordersTherapeutic drug monitoringPharmacogeneticsPharmacogenomicsDrug Monitoringbusinesscomputerdescription
Psychiatry is increasingly combining new pharmacogenomic findings with therapeutic drug monitoring (TDM) to improve the safety and efficacy of pharmacotherapy. However, a distinction should be made between “nice to know” and “need to know” pharmacogenomic data because many results are statistically significant in meta-analyses but are not clinically relevant due to their low effect sizes. Some examples will illustrate this integration.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-11-06 | Clinical pharmacology and therapeutics |