6533b85efe1ef96bd12bfb1a
RESEARCH PRODUCT
Heat-Shock Proteins in Sea Urchin Embryos
Gabriella SconzoMaria Di BernardoGiovanni GiudiceGiovanni GiudiceA.m. PirroneMarta Di CarloMaria Carmela RoccheriRoberto Gambinosubject
Cancer Researchanimal structuresbiologyMesenchymeTranslation (biology)EmbryoCell BiologySea urchin embryobiology.organism_classificationBlastulaCell biologymedicine.anatomical_structureHeat shock proteinembryonic structuresBotanymedicineProtein biosynthesisPluteusMolecular BiologyDevelopmental Biologydescription
The production of heat-shock proteins in sea urchin embryos is accompanied by the appearance at the polysomal level of their relative mRNAs, as shown by their translation in a cell-free system; thus suggesting that the regulation of their production occurs at a transcriptional level. The mechanism for the inhibition of the bulk protein synthesis and for its reversal on the other hand should be looked for at a posttranscriptional level, since both these phenomena occur also in the presence of actinomycin D. The heat-shock proteins produced as early as at the mesenchyme blastula stage persist within the embryo at least till the pluteus stage.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1982-09-01 | Differentiation |