6533b85efe1ef96bd12bff93
RESEARCH PRODUCT
Monte Carlo analysis of polymer translocation with deterministic and noisy electric fields
Dominique Persano AdornoBernardo SpagnoloSalvatore ZammitoG. DenaroNicola PizzolatoDavide Valentisubject
Materials scienceQC1-999transport dynamics of biomoleculeMonte Carlo methodpolymer moleculespolymer moleculeGeneral Physics and AstronomyQuantitative Biology::Subcellular ProcessesPiecewise linear functionmonte carlo simulationsnoise in biological systemChain (algebraic topology)Electric fieldStatistical physicschemistry.chemical_classificationPhysics::Biological PhysicsQuantitative Biology::Biomoleculestransport dynamics of biomoleculesPhysicsPolymernoise in biological systemsNanoporechemistryChemical physicsCommunication channelVoltagedescription
AbstractPolymer translocation through the nanochannel is studied by means of a Monte Carlo approach, in the presence of a static or oscillating external electric voltage. The polymer is described as a chain molecule according to the two-dimensional “bond fluctuation model”. It moves through a piecewise linear channel, which mimics a nanopore in a biological membrane. The monomers of the chain interact with the walls of the channel, modelled as a reflecting barrier. We analyze the polymer dynamics, concentrating on the translocation time through the channel, when an external electric field is applied. By introducing a source of coloured noise, we analyze the effect of correlated random fluctuations on the polymer translocation dynamics.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-06-01 | Open Physics |