6533b85efe1ef96bd12c08a8

RESEARCH PRODUCT

3D-Printed Solid Dispersion Drug Products.

Bahijja Tolulope Raimi-abrahamLaura Modica De MohacLaura Modica De MohacSuet Li Chew

subject

Drug3d printedMaterials sciencemedia_common.quotation_subjecteducationPharmaceutical Science3D printing02 engineering and technology030226 pharmacology & pharmacyPolyvinyl alcoholArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineamorphous solid dispersionfixed dose combinationmedia_commonbusiness.industry3D printing021001 nanoscience & nanotechnologySolventpoor solubilitychemistryChemical engineeringDrug deliveryManufacturing methods0210 nano-technologybusinessDispersion (chemistry)additive manufacturing

description

With the well-known advantages of additive manufacturing methods such as three-dimensional (3D) printing in drug delivery, it is disappointing that only one product has been successful in achieving regulatory approval in the past few years. Further research and development is required in this area to introduce more 3D printed products into the market. Our study investigates the potential of fixed dose combination solid dispersion drug products generated via 3D printing. Two model drugs&mdash

10.3390/pharmaceutics11120672https://pubmed.ncbi.nlm.nih.gov/31835682