A randomized, open-label, two-arm phase II trial comparing the efficacy of sequential ipilimumab (ipi) versus best supportive care (BSC) following first-line (1L) chemotherapy in patients with unresectable, locally advanced/metastatic (A/M) gastric or gastro-esophageal junction (G/GEJ) cancer.

6533b85ffe1ef96bd12c0f68

RESEARCH PRODUCT

A randomized, open-label, two-arm phase II trial comparing the efficacy of sequential ipilimumab (ipi) versus best supportive care (BSC) following first-line (1L) chemotherapy in patients with unresectable, locally advanced/metastatic (A/M) gastric or gastro-esophageal junction (G/GEJ) cancer.

Maria Teresa Kong-sanchez Markus Moehler Jin Won Kim Jae Yong Cho Yung-jue Bang Agnes Balogh Yeul Hong Kim Maria Di Bartolomeo Kensei Yamaguchi Jaffer A. Ajani

subject

0301 basic medicine Oncology Cancer Research medicine.medical_specialty First line medicine.medical_treatment Gastro esophageal junction Locally advanced Ipilimumab 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Internal medicine medicine In patient Chemotherapy business.industry Cancer medicine.disease Surgery 030104 developmental biology Oncology 030220 oncology & carcinogenesis Open label business medicine.drug

description

4011Background: Pts with advanced gastric cancer have a poor prognosis with median overall survival (OS) of ~1 yr. Ipi is a monoclonal antibody that enhances T-cell activation and T-effector cell t...

year	journal	country	edition	language
2016-05-20	Journal of Clinical Oncology

https://doi.org/10.1200/jco.2016.34.15_suppl.4011

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