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RESEARCH PRODUCT
Vitamin d and psoriasis pathology in the mediterranean region, valencia (Spain)
Nuria Rubio-lópezMaría Morales Suárez-varelaAgustín Llopis-gonzálezWilliam B. GrantPaloma Reguera-lealsubject
VitaminAdultMalemedicine.medical_specialtyVitaminesHealth Toxicology and MutagenesisPopulationlcsh:Medicinevitamin Dvitamin D deficiencyArticlechemistry.chemical_compoundYoung AdultPsoriasisInternal medicineVitamin D and neurologymedicineOdds RatioHumansMediterranean regioneducationCholecalciferoleducation.field_of_studybusiness.industrylcsh:RPublic Health Environmental and Occupational HealthPellOdds ratiopsoriasisMiddle Agedmedicine.diseaseVitamin D DeficiencyDermatologiaEndocrinologychemistrySpainCase-Control StudiesErgocalciferolsFemaleMetabolic syndromebusinessCholecalciferoldietdescription
Vitamin D has important immunomodulatory effects on psoriasis in the Mediterranean region. To measure vitamin D intake in subjects with and without psoriasis, and to find an association with relevant clinical features, a case-control study was performed using cases (n = 50, 50% participation rate) clinically diagnosed with psoriasis and 200 healthy subjects (39.5% participation rate), leaving a final sample of 104 people. A survey was conducted using a food frequency questionnaire and clinical histories. Cases and controls were compared using univariate and multivariate analyses. We observed insufficient intake of cholecalciferol (vitamin D3) or ergocalciferol (vitamin D2) for both cases and controls. Patients with psoriasis were at greater risk of associated pathologies: dyslipidaemia (OR: 3.6, 95% CI: 0.8–15.2)
year | journal | country | edition | language |
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2014-11-25 |