6533b860fe1ef96bd12c305f

RESEARCH PRODUCT

IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss

Carlos Romá-mateoCarlos Romá-mateoAdelaida M. CelayaAdelaida M. CelayaLourdes Rodriguez-de La RosaLourdes Rodriguez-de La RosaLourdes Rodriguez-de La RosaIsabel Varela-nietoIsabel Varela-nietoIsabel Varela-nietoJosé Manuel ZubeldiaJose M Bermúdez-muñozJose M Bermúdez-muñozCarlos AvendañoCarlos AvendañoFederico PallardóFederico V. Pallardó

subject

0301 basic medicineAgingApoptosisHaploinsufficiencyMice0302 clinical medicineBiology (General)Insulin-Like Growth Factor ICell DeathapoptosisGeneral Medicine3. Good healthCochleaCytokinesmedicine.symptomHaploinsufficiencyNoise-induced hearing lossmedicine.medical_specialtyHeterozygoteHearing lossQH301-705.5InflammationArticleARHLProinflammatory cytokine03 medical and health sciencesInternal medicinemedicineotorhinolaryngologic diseasesAnimalsRNA MessengerProtein kinase BCochleaInflammationbusiness.industryGene Expression ProfilingAKTTGFβ1Auditory Thresholdmedicine.diseaseOxidative Stress030104 developmental biologyEndocrinologyGene Expression RegulationHearing Loss Noise-InducedAgeingSynapsesIL1βJNKbusinessNoise030217 neurology & neurosurgeryBiomarkersNIHL

description

This article belongs to the Collection Insulin-Like Growth Factors in Development, Cancers and Aging.

yearjournalcountryeditionlanguage
2021-07-01
10.3390/cells10071686http://hdl.handle.net/10261/259393