6533b861fe1ef96bd12c56c5

RESEARCH PRODUCT

Electrochemical carboxylation of benzal chloride

Giuseppe SilvestriAntonio GulottaG. GrecoGiuseppe FilardoSalvatore Gambino

subject

chemistry.chemical_classificationChemistryDecarboxylationCarboxylic acidOrganic ChemistryInorganic chemistrychemistry.chemical_elementPhenylacetic acidElectrochemistryBiochemistrychemistry.chemical_compoundDicarboxylic acidCarboxylationAluminiumDrug DiscoveryBenzal chloride

description

Abstract The clectrocarboxylation of benzal chloride to -chlorophenylacetic and phenylmalonic acids is realized in diaphragmless cells with aluminium sacrificial anodes. Yields respectively up to 50% and 30% can be obtained. Phenylacetic acid is always present among the products.

https://doi.org/10.1016/s0040-4039(01)81424-6