6533b862fe1ef96bd12c6550
RESEARCH PRODUCT
A new method for the placement of brachytherapy probes in paranasal sinus and nasopharynx neoplasms
Bernd KremerRalph MösgesDimetrios AndreopoulosLudger Klimeksubject
AdultCancer Researchmedicine.medical_specialtyPalliative treatmentNasopharynx Neoplasmsmedicine.medical_treatmentBrachytherapyBrachytherapyHumansMedicineRadiology Nuclear Medicine and imagingSinus (anatomy)AgedRadiationbusiness.industryComputer aidCarcinomaNasopharyngeal NeoplasmsEquipment DesignMiddle AgedRadiotherapy Computer-AssistedRadiation therapymedicine.anatomical_structureParanasal sinusesOncologyCarcinoma Squamous CellRadiologyNeoplasm Recurrence LocalTomography X-Ray ComputedbusinessParanasal Sinus Neoplasmsdescription
Abstract Purpose: In afterloading therapy, the exact placement of the applicator is crucial for the result of radiotherapy. A deviation of few millimeters from the target leads to a significant reduction of radiation energy to the tumor. Methods and Materials: We present a new method using a computer-assisted device for three-dimensional placing of afterloading probes based on CT scans that allows for the exact placement. Results: Target points have been reached with an accuracy of 0.6 mm. Since 1991 we have used this technique for 24 clinical applications in 11 patients with recurrent neoplasms in the region of the paranasal sinuses and nasopharynx for palliative treatment. Conclusions: The presented method is a reliable and precise procedure for the positioning of afterloading probes, avoiding the inaccuracy of the traditional methods.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-03-01 | International Journal of Radiation Oncology*Biology*Physics |