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RESEARCH PRODUCT
Necrobiotic xanthogranuloma. Differential diagnosis, treatment and systemic involvement. Case report
Manuel Díaz-llopisM. Chirivella-casanovaEdgar M. EspanaM.j. López-pratsJ. AviñóE. Sanz-marcosubject
medicine.medical_specialtyAbstract caseTriamcinolone acetonidemedicine.diagnostic_testIgG.monoclonalbusiness.industryGeneral Medicinemedicine.diseaseDermatologyeye diseasesmedicine.anatomical_structureBiopsymedicineDifferential diagnosisbusinessNecrobiotic xanthogranulomaEyelid edemaOrbit (anatomy)medicine.drugdescription
Abstract Case report A 48-year-old male was referred to our hospital for further evaluation of eyelid edema with bilateral yellowish ulcerated nodules. Suspecting a xanthogranulomatosis, imaging tests and biopsy were performed with diagnosis of necrobiotic xanthogranuloma. IgG monoclonal gammapathy was diagnosed in a systemic study. Systemic corticosteroids and cyclosporine were initiated unsuccessfully; therefore, intra-lesional injections of triamcinolone were started, which controlled the orbital disease. Discussion Necrobiotic xanthogranuloma is a rare condition that usually affects the eyelids and anterior orbit. Its diagnosis is important as it is associated with malignant lymphoproliferative processes. Intra-lesional corticosteroids were effective in our patient.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-05-01 | Archivos de la Sociedad Española de Oftalmología (English Edition) |