6533b862fe1ef96bd12c6dcb

RESEARCH PRODUCT

Amino acid transport in the retina.

Federico PiccoliFederico PiccoliRosa GuarneriRosa GuarneriFrancesco PonteFrancesco PonteVincenzo BonavitaVincenzo Bonavita

subject

LysineGlycinechemistry.chemical_elementBiologyInhibitory postsynaptic potentialBiochemistryOxygenRetinaCellular and Molecular NeuroscienceGlutamatesmedicineAnimalsAmino AcidsInhibitory effectchemistry.chemical_classificationRetinaLysineGlutamate receptorBiological TransportGeneral MedicineAmino acidRatsKineticsmedicine.anatomical_structurechemistryBiochemistryGlycine

description

The uptake, exit, homoexchange, inhibitory pattern, and kinetic analysis of transport of three amino acids were studied in the isolated retina of adult rat under different metabolic conditions. Only in the case of glycine, uptake and exit were shown to duplicate the processes observed in brain slices. In the case of lysine, glucose and oxygen showed an inhibitory effect, but with glutamate spontaneous exit could not be measured. It was also found that the rate of homoexchange for glycine and glutamate, but not for lysine, increases in the presence of oxygen and glucose.

yearjournalcountryeditionlanguage
1978-06-01Neurochemical research
10.1007/bf00965582https://pubmed.ncbi.nlm.nih.gov/745654