6533b86cfe1ef96bd12c82a4

RESEARCH PRODUCT

Reference Values of Thyroid Hormones During the First Trimester of Pregnancy in Valencian Community (Spain) and Their Relationship with Iodine Intake

Maria Teresa Murillo-llorenteCarmen Fajardo-montañanaMarcelino Pérez-bermejo

subject

Adultendocrine systemendocrine system diseasesNutritional Statuschemistry.chemical_elementPhysiology030209 endocrinology & metabolismlcsh:TX341-641Thyroid Function TestsIodineArticleEating03 medical and health sciences0302 clinical medicineThyroid-stimulating hormonegestationPregnancymedicineHumans030212 general & internal medicineSodium Chloride Dietarythyroid hormonesiodine deficiencyPregnancyNutrition and Dieteticsbusiness.industryThyroidioduriaMaternal Nutritional Physiological Phenomenareference valuesmedicine.diseaseIodine deficiencyiodized saltHealthy VolunteersPregnancy Trimester FirstIodised saltCross-Sectional Studiesmedicine.anatomical_structurechemistrySpainReference valuesDietary SupplementsGestationFemalebusinesslcsh:Nutrition. Foods and food supplyhormones hormone substitutes and hormone antagonistsIodineFood Science

description

Thyroid hormones require special monitoring during the first trimester of gestation. Local reference values should be applied if available, especially in iodine-deficient areas, as generalized iodine supplementation is controversial. The aim of the present study was to establish thyroid stimulating hormone (TSH) and free thyroxine (FT4) reference values in the first trimester of gestation in the Valencian community (Spain) and relate them to iodine intake. A total of 261 healthy pregnant women participated in the study. The calculated reference values were 0.128&ndash

10.3390/nu12051433https://www.mdpi.com/2072-6643/12/5/1433