6533b86cfe1ef96bd12c8353

RESEARCH PRODUCT

Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders

M SavareseMarta CarettoTommaso SimonciniR. LeccaCarolina LombardiFederica ProviniDanila CarusoEnrica BonanniM. C. SpaggiariRosalia SilvestriMichelangelo MaestriMaria R. BonsignoreM. MiccoliMonica PulighedduIrene AricòM.c. Di PerriS. GallettaLaura Palagini

subject

Sleep Initiation and Maintenance Disordermedicine.medical_treatmentSerotonin and Noradrenaline Reuptake InhibitorPosition statementSleep medicine0302 clinical medicineSleep Initiation and Maintenance DisordersCognitive behavioraltherapy for insomnia (CBT-I)InsomniaSleep Wake Disorder030212 general & internal medicineContinuous positive airway pressureRestless legs syndromeSerotonin and Noradrenaline Reuptake InhibitorsCognitive behavioraltherapy for insomnia (CBT-I); Hormonereplacementtherapy (HRT); Menopause; Position statement; Sleepdisorders; Vasomotorsymptoms (VMS)Sleep Apnea Obstructive030219 obstetrics & reproductive medicineContinuous Positive Airway PressureDepressionObstetrics and GynecologySerotonin Uptake InhibitorAntidepressive AgentsMenopauseCognitive behavioral therapyCognitive behavioral therapy for insomnia (CBT-I)SleepdisordersAntidepressive AgentFemalemedicine.symptomMenopauseSelective Serotonin Reuptake Inhibitorsmedicine.drugHumanSleep Wake Disordersmedicine.medical_specialtyHormone Replacement TherapyVasomotor symptoms (VMS)MirtazapineCognitive behavioral therapy for insomnia (CBT-I); Hormone replacement therapy (HRT); Menopause; Position statement; Sleep disorders; Vasomotor symptoms (VMS); Antidepressive Agents; Cognitive Behavioral Therapy; Continuous Positive Airway Pressure; Depression; Exercise; Female; Humans; Mirtazapine; Quality of Life; Restless Legs Syndrome; Serotonin Uptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sleep; Sleep Apnea Obstructive; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Hormone Replacement Therapy; MenopauseMirtazapineSettore MED/10 - Malattie Dell'Apparato RespiratorioHormone replacement therapy (HRT)Hormonereplacementtherapy (HRT)General Biochemistry Genetics and Molecular Biology03 medical and health sciencesRestless Legs Syndromemental disordersmedicineHumansExerciseSleep disorderCognitive Behavioral Therapybusiness.industryVasomotorsymptoms (VMS)medicine.diseasenervous system diseasesObstructive sleep apneaMenopause sleep disorders vasomotor symptoms (VMS) hormone replacement therapy (HRT) Cognitive Behavioral Therapy for Insomnia (CBT-I) Position StatementPhysical therapyQuality of LifebusinessSleep

description

Insomnia, vasomotor symptoms (VMS) and depression often co-occur after the menopause, with consequent health problems and reductions in quality of life. The aim of this position statement is to provide evidence-based advice on the management of postmenopausal sleep disorders derived from a systematic review of the literature. The latter yielded results on VMS, insomnia, circadian rhythm disorders, obstructive sleep apnea (OSA) and restless leg syndrome (RLS). Overall, the studies show that menopausal hormone therapy (MHT) improves VMS, insomnia, and mood. Several antidepressants can improve insomnia, either on their own or in association with MHT; these include selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), and mirtazapine. Long-term benefits for postmenopausal insomnia may also be achieved with non-drug strategies such as cognitive behavioral therapy (CBT) and aerobic exercise. Continuous positive airway pressure (CPAP) and mandibular advancement devices (MADs) both reduce blood pressure and cortisol levels in postmenopausal women suffering from OSA. However, the data regarding MHT on postmenopausal restless legs syndrome are conflicting.

10.1016/j.maturitas.2019.08.006http://hdl.handle.net/11585/718823