0000000000131796

AUTHOR

Monica Puligheddu

showing 5 related works from this author

REM sleep behavior disorder and periodic leg movements in sleep in patients with amyotrophic lateral sclerosis

2013

Introduction In the last few years, it has been increasingly recognized that patients with amyotrophic lateral sclerosis (ALS) frequently suffer of sleep-related complaints, including insomnia, restless legs syndrome, and daytime sleepiness, although, in the past, many of the nocturnal symptoms have been mainly ascribed to chronic respiratory insufficiency and hypoventilation. In addition, excluding few single cases reported, polysomnographic studies did not look for abnormal motor activity during sleep that could be indicative of Rapid Eye Movements (REM) sleep behavior disorder (RBD) and REM sleep without atonia (RSWA), which are highly prevalent in other neurodegenerative disorders with …

Sleep disorderPediatricsmedicine.medical_specialtyGeneral Medicinemedicine.diseaseSleep in non-human animalsNon-rapid eye movement sleepREM sleep behavior disorderAnesthesiamedicineInsomniaRestless legs syndromemedicine.symptomSleep onsetPsychologySlow-wave sleepSleep Medicine
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REM sleep behavior disorder and periodic leg movements during sleep in ALS

2017

Objective To assess sleep characteristics and the occurrence of abnormal muscle activity during sleep, such as REM sleep without atonia (RSWA), REM sleep behavior disorder (RBD), and periodic leg movements during sleep (PLMS), in patients with amyotrophic lateral sclerosis (ALS). Methods A total of 41 patients with ALS and 26 healthy subjects were submitted to clinical interview and overnight video-polysomnography. Results A total of 22 patients with ALS (53.6%) reported poor sleep quality. Polysomnographic studies showed that patients with ALS had reduced total sleep time, increased wakefulness after sleep onset, shortened REM and slow-wave sleep, and decreased sleep efficiency, compared t…

Malemedicine.medical_specialtyNeurologyperiodic leg movementPolysomnography[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologySleep StagePolysomnographyREM Sleep Behavior Disorderrapid eye movement sleep without atoniaNon-rapid eye movement sleepREM sleep behavior disorder03 medical and health sciences0302 clinical medicineInsomniamedicineHumansamyotrophic lateral sclerosisleepComputingMilieux_MISCELLANEOUSSlow-wave sleepAgedmedicine.diagnostic_test[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior[SCCO.NEUR]Cognitive science/NeuroscienceAmyotrophic Lateral Sclerosis[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesGeneral MedicineMiddle Agedmedicine.diseaseSleep in non-human animals3. Good healthNocturnal Myoclonus Syndrome030228 respiratory systemItalyNeurologyAnesthesiarapid eye movement sleep behavior disorderFemaleSettore MED/26 - NeurologiaSleep StagesNeurology (clinical)medicine.symptomSleep onsetPsychology030217 neurology & neurosurgeryHuman
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Pre-sleep arousal and sleep quality during the COVID-19 lockdown in Italy

2021

Abstract Objective The COVID-19 pandemic has strongly affected daily habits and psychological wellbeing, and many studies point to large modifications in several sleep and sleep-related domains. Nevertheless, pre-sleep arousal during the pandemic has been substantially overlooked. Since hyperarousal represents one of the main factors for the development and the perpetuation of chronic insomnia disorder, the assessment of variables associated with high levels of pre-sleep arousal during the pandemic is clinically relevant. The study aimed to assess the prevalence and predictors of perceived sleep quality and pre-sleep arousal in an Italian sample during the COVID-19 lockdown. Methods We used…

stress depressionCOVID-19 pandemic; Depression; Pre-sleep arousal; Sleep quality; Stress.Coronavirus disease 2019 (COVID-19)Pre sleep arousalStreSocio-culturaleCOVID-19 pandemicSettore MED/10 - Malattie Dell'Apparato RespiratorioStressArousalCOVID-19 pandemic; Depression; Pre-sleep arousal; Sleep quality; Stress; Arousal; Communicable Disease Control; Humans; Pandemics; SARS-CoV-2; Sleep; Sleep Quality; Surveys and Questionnaires; COVID-19; Sleep Initiation and Maintenance DisordersSurveys and QuestionnairesSleep Initiation and Maintenance DisordersInsomniamedicineHumansSurveys and QuestionnairePandemicsPre-sleep arousalDepression (differential diagnoses)Sleep qualityPandemicbusiness.industryDepressionSARS-CoV-2COVID-19CognitionGeneral MedicineSleep qualitySleep in non-human animalsCOVID-19 pandemic; sleep quality; pre-sleep arousal; stress depressionCommunicable Disease ControlOriginal Articlemedicine.symptombusinessArousalSleepClinical psychologyHuman
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Brivaracetam as add-on treatment in patients with post-stroke epilepsy: real-world data from the BRIVAracetam add-on First Italian netwoRk Study (BRI…

2022

Objective: Post-stroke epilepsy (PSE) is one of the most common causes of acquired epilepsy and accounts for about 10-15% of all newly diagnosed epilepsy cases. However, evidence about the clinical profile of antiseizure medications in the PSE setting is currently limited. Brivaracetam (BRV) is a rationally developed compound characterized by high-affinity binding to synaptic vesicle protein 2A. The aim of this study was to assess the 12-month effectiveness and tolerability of adjunctive BRV in patients with PSE treated in a real-world setting. Methods: This was a subgroup analysis of patients with PSE included in the BRIVAracetam add-on First Italian netwoRk Study (BRIVAFIRST). The BRIVAFI…

AdultAntiseizure medication; Brivaracetam; Cerebrovascular diseases; Focal seizures; StrokeCerebrovascular diseasesSettore MED/26Antiseizure medication Brivaracetam Focal seizures Stroke Cerebrovascular diseasesFocal seizuresDouble-Blind MethodDrug TherapySeizuresHumansAgedRetrospective StudiesAntiseizure medicationEpilepsyGeneral MedicineMiddle AgedPyrrolidinonesStrokeTreatment OutcomeNeurologyItalyCombinationBrivaracetamAntiseizure medication; Brivaracetam; Cerebrovascular diseases; Focal seizures; Stroke; Adult; Aged; Anticonvulsants; Double-Blind Method; Drug Therapy Combination; Humans; Italy; Middle Aged; Pyrrolidinones; Retrospective Studies; Seizures; Treatment Outcome; Epilepsy; StrokeDrug Therapy CombinationAnticonvulsantsNeurology (clinical)
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Italian Association of Sleep Medicine (AIMS) position statement and guideline on the treatment of menopausal sleep disorders

2019

Insomnia, vasomotor symptoms (VMS) and depression often co-occur after the menopause, with consequent health problems and reductions in quality of life. The aim of this position statement is to provide evidence-based advice on the management of postmenopausal sleep disorders derived from a systematic review of the literature. The latter yielded results on VMS, insomnia, circadian rhythm disorders, obstructive sleep apnea (OSA) and restless leg syndrome (RLS). Overall, the studies show that menopausal hormone therapy (MHT) improves VMS, insomnia, and mood. Several antidepressants can improve insomnia, either on their own or in association with MHT; these include selective serotonin reuptake …

Sleep Initiation and Maintenance Disordermedicine.medical_treatmentSerotonin and Noradrenaline Reuptake InhibitorPosition statementSleep medicine0302 clinical medicineSleep Initiation and Maintenance DisordersCognitive behavioraltherapy for insomnia (CBT-I)InsomniaSleep Wake Disorder030212 general & internal medicineContinuous positive airway pressureRestless legs syndromeSerotonin and Noradrenaline Reuptake InhibitorsCognitive behavioraltherapy for insomnia (CBT-I); Hormonereplacementtherapy (HRT); Menopause; Position statement; Sleepdisorders; Vasomotorsymptoms (VMS)Sleep Apnea Obstructive030219 obstetrics & reproductive medicineContinuous Positive Airway PressureDepressionObstetrics and GynecologySerotonin Uptake InhibitorAntidepressive AgentsMenopauseCognitive behavioral therapyCognitive behavioral therapy for insomnia (CBT-I)SleepdisordersAntidepressive AgentFemalemedicine.symptomMenopauseSelective Serotonin Reuptake Inhibitorsmedicine.drugHumanSleep Wake Disordersmedicine.medical_specialtyHormone Replacement TherapyVasomotor symptoms (VMS)MirtazapineCognitive behavioral therapy for insomnia (CBT-I); Hormone replacement therapy (HRT); Menopause; Position statement; Sleep disorders; Vasomotor symptoms (VMS); Antidepressive Agents; Cognitive Behavioral Therapy; Continuous Positive Airway Pressure; Depression; Exercise; Female; Humans; Mirtazapine; Quality of Life; Restless Legs Syndrome; Serotonin Uptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Sleep; Sleep Apnea Obstructive; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Hormone Replacement Therapy; MenopauseMirtazapineSettore MED/10 - Malattie Dell'Apparato RespiratorioHormone replacement therapy (HRT)Hormonereplacementtherapy (HRT)General Biochemistry Genetics and Molecular Biology03 medical and health sciencesRestless Legs Syndromemental disordersmedicineHumansExerciseSleep disorderCognitive Behavioral Therapybusiness.industryVasomotorsymptoms (VMS)medicine.diseasenervous system diseasesObstructive sleep apneaMenopause sleep disorders vasomotor symptoms (VMS) hormone replacement therapy (HRT) Cognitive Behavioral Therapy for Insomnia (CBT-I) Position StatementPhysical therapyQuality of LifebusinessSleep
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