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RESEARCH PRODUCT
Synthesis of Highly Functionalized N , N ‐Diarylamides by an Anodic C, N ‐Coupling Reaction
Siegfried R. WaldvogelRobert FrankeSebastian LipsMaurice DörrCarlos A. Martínez-huitleCarlos A. Martínez-huitleDieter Schollmeyersubject
Green chemistry010405 organic chemistryChemistryOrganic ChemistryGeneral ChemistryElectrolyte010402 general chemistryElectrosynthesisElectrochemistry01 natural sciencesCombinatorial chemistryCatalysisCoupling reaction0104 chemical sciencesAnodeConstant currentdescription
We report an innovative, sustainable and straightforward protocol for the synthesis of N,N-diarylamides equipped with nonprotected hydroxyl groups by using electrosynthesis. The concept allows the application of various substrates furnishing diarylamides with yields up to 57 % within a single and direct electrolytic protocol. The method is thereby easy to conduct in an undivided cell with constant current conditions offering a versatile and short-cut alternative to conventional pathways.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-05-13 | Chemistry – A European Journal |