6533b86cfe1ef96bd12c8979

RESEARCH PRODUCT

In vitro studies of methanol and dichloromethanol extracts ofJuniperus oxycedrus L.

R. BelloJ. EsplugesL. MorenoEduardo Primo-yúfera

subject

PharmacologyFolk medicineTraditional medicineBiological activityBiologyPharmacognosybiology.organism_classificationIn vitrochemistry.chemical_compoundchemistryBotanymedicineMethanolJuniperus oxycedrusHistamineAcetylcholinemedicine.drug

description

The present study evaluated the effect of methanol and dichloromethanol extracts obtained from the leaves and stems of Juniperus oxycedrus against neurotransmitter-induced contraction in different isolated tissues of rats and guinea-pigs. Diverse concentrations of these extracts inhibit the concentration curve response to histamine, serotonin and acetylcholine. These results contribute to explaining the use of this plant in folk medicine. © 1997 John Wiley & Sons, Ltd.

https://doi.org/10.1002/(sici)1099-1573(199706)11:4<309::aid-ptr87>3.0.co;2-6