6533b86cfe1ef96bd12c8b03

RESEARCH PRODUCT

Non-Immune Goiter and Hypothyroidism in a 19-Week Fetus: A Plea for Conservative Treatment

Joachim PohlenzDiane FrancoeurNathalie AlosGuy Van VlietAndrée GrignonJohnny DeladoëyPia HermannsSophie Stoppa-vaucher

subject

AdultMalePolyhydramniosendocrine systemmedicine.medical_specialtyPediatricsPolyhydramniosGoiterAmniotic fluidendocrine system diseasesLevothyroxineThyrotropinUltrasonography PrenatalThyroid-stimulating hormonePregnancyCongenital HypothyroidismmedicineHumansFetusPregnancyGoiterbusiness.industryAmniotic Fluidmedicine.diseaseSurgeryCongenital hypothyroidismFetal DiseasesThyroxinePregnancy Trimester SecondPediatrics Perinatology and Child HealthFemaleCordocentesisbusinesshormones hormone substitutes and hormone antagonistsmedicine.drug

description

Hypothyroidism was documented by cordocentesis at 19 weeks in a fetus with non-immune goiter. Intra-amniotic thyroxine was injected at 25 weeks when amniotic fluid volume increased. Psychomotor outcome was normal. We argue that intra-amniotic thyroxine should not be used to treat the hypothyroidism but only to correct the development of polyhydramnios.

yearjournalcountryeditionlanguage
2009-10-02The Journal of Pediatrics
https://doi.org/10.1016/j.jpeds.2010.01.018