6533b86cfe1ef96bd12c8bfa

RESEARCH PRODUCT

The reconstructive role of TachoSil in neurosurgery

Luigi BasileGraziano FrancescaMaugeri RosarioIacopino D. GerardoCarlo Gulì

subject

medicine.medical_specialtyFistulalcsh:Surgery030204 cardiovascular system & hematologylcsh:RC346-429Fibrin03 medical and health sciences0302 clinical medicineMedicineCsf leakagelcsh:Neurology. Diseases of the nervous systembiologySettore MED/27 - Neurochirurgiabusiness.industrylcsh:RD1-811TachoSilSurgical proceduresmedicine.diseaseTachosilSurgeryHemostasisbiology.proteinSurgeryDural closureNeurology (clinical)Neurosurgerybusiness030217 neurology & neurosurgery

description

Abstract Hemorrhages, cerebrospinal fluid (CSF) fistula and infections are the most challenging post-operative complications in Neurosurgery [1–5]. Fibrin sealant agents have been developed with the aim to provide efficient hemostasis and safe dural closure [3,6–14]. In this study we report our initial experience using TachoSil® (haemostatic surgical patch; Nycomed, Linz, Austria) in achieving hemostasis and CSF leakage repair during cranio-cerebral procedures [15–18]. We describe and show the unique features of this fibrin sealant, pioneered with stunning success in many surgical procedures known to be at high risk of peri- and postoperative bleeding (i.e. nephrectomies, pulmonary lobectomies, ballistic injuries, arthroplasties, coronary bypass graftings), but still not widely exploited at its best in the field of Neurosurgery.

10.1016/j.inat.2016.08.002http://dx.doi.org/10.1016/j.inat.2016.08.002