Staphylococcus epidermidis virulences faktori un epidemioloģiskā nozīme

6533b86cfe1ef96bd12c8f97

RESEARCH PRODUCT

Staphylococcus epidermidis virulences faktori un epidemioloģiskā nozīme

subject

meticilīnrezistence methicillin resistance genotyping virulence factors Medicine genotipēšana S.epidermidis Veselības aprūpe Medicīna staphylococci

description

Staphylococcus epidermidis svarīgākais virule nces faktors ir biofilmas veidošana. Lai diferencētu komensālos celmus no kolonizējošiem un invazīviem celmiem, pētījumā tika izmantotas fenotipiskās metodes, nosakot biofilmas veidošanu, antibiogrammu, un molekulārās bioloģijas metodes, nosakot virulences gēnus aap / ica A un mec A. Rezultāti liecina, ka biofilmu veidošana raksturīga klīniskajiem celmiem, statistiski ticami biežāk gēni aap/ica A bija noteikti klīniskajos S.epidermidis celmos, tie vis biežāk bija rezistenti pret meticilīnu (97,8%). S.epidermidis tipēšanai pirmo reizi tika pielietota MLST (multilokusu sekvenču tipēšana) metode. Pētījuma rezultāti ļauj secināt par S.epidermidis genotipisko dažādību un spēju iegūt meticilīnrezistenci īsā laika periodā, cilvēkam atrodoties hospitalajā vidē. Atslēgvārdi: S.epidermidis , meticilī nrezistence, virulences faktori, genotipēšana

year	journal	country	edition	language
2016-01-01

https://dspace.lu.lv/dspace/handle/7/34504

PEPhysical Sciences and Engineering
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