6533b86dfe1ef96bd12c9807
RESEARCH PRODUCT
Chameleonic appearance of caseous calcification of the mitral valve – still a problem for its appropriate management
Florin GrosuAdrian CostacheAna LascuAndrei Gheorghe Marius MotocCiprian Nicuşor DimaCaius Glad StreianRaluca ŞOşdeansubject
Embryologymedicine.medical_specialtyHeart Valve DiseasesCase ReportPathology and Forensic Medicinemitral calcificationCardiac magnetic resonance imagingMitral valvemedicineAnimalsHumanscaseous calcificationMitral Valve Annuluscardiovascular diseasesMitral annulusmedicine.diagnostic_testbusiness.industrymitral annulusCell BiologyGeneral MedicineMiddle Agedmedicine.diseaseFibrous connective tissuemyxoid structuremedicine.anatomical_structurePapillary fibroelastomacardiovascular systemMitral ValveFemaleRadiologyDifferential diagnosisbusinessDevelopmental BiologyCalcificationdescription
According to the research literature, the caseous calcification of the mitral annulus (CCMA) is a rare variant of the mitral annulus calcification (MAC) entity, described mostly in elderly women. The aim of this study was to present the case of a 53-year-old female patient with caseous calcification of the mitral valve annulus and posterior cusp, which was diagnosed as papillary fibroelastoma. An echo-dense and quasi-homogeneous tumoral mass, measuring 1.6/1.4 cm, at the level of the posterior mitral ring was detected by echocardiographic examination, as well as by cardiac magnetic resonance imaging (MRI). Histopathological analysis revealed fibrous connective tissue with myxoid areas, hyaline degeneration with unstructured necrosis and dystrophic calcifications, which was consisting with the operative findings of a “toothpaste tumor”, or caseous calcification of the mitral valve. Differential diagnosis with other cardiac tumors, abscesses, thrombi or fibroelastomas is emphasized.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-02-05 | Romanian Journal of Morphology and Embryology |