6533b86dfe1ef96bd12ca047

RESEARCH PRODUCT

Scuteparvin, a new neoclerodane diterpenoid from Scutellaria parvula

Orietta ServettazAntonella MaggioMaurizio BrunoSergio RosselliFranco PiozziLeonardo Scaglioni

subject

biologyStereochemistryneoclerodaneScutellaria parvulabiology.organism_classificationBiochemistryditerpeneTerpenoidAjugalamiaceaeScutellaria parvulaBotanyScutellariaEcology Evolution Behavior and Systematics

description

Abstract The diterpenoid fraction occurring in the acetone extract of the aerial parts of Scutellaria parvula has been investigated. Only one neoclerodane diterpenoid, scuteparvin, was isolated and its structure elucidated as 4α,18-epoxy-6α- trans -cinnamoyloxy- neo clerod-13-en-15,16-olide, a new natural product. Scuteparvin is quite similar to the already known ajugarin V from Ajuga remota , the only difference being the occurrence of a trans -cinnamoyl ester system instead of an acetate on the 6α-OH group. This finding confirms that the genera Scutellaria and Ajuga are closely related taxonomically.

yearjournalcountryeditionlanguage
2004-08-01Biochemical Systematics and Ecology
https://doi.org/10.1016/j.bse.2004.01.002