6533b86dfe1ef96bd12ca07a

RESEARCH PRODUCT

Manganese(II) complexes of scorpiand-like azamacrocycles as MnSOD mimics.

Antonio DoménechJulio LatorreLucas Del Castillo AgudoMario InclánConxa SorianoEnrique García-españaMa Paz ClaresSalvador BlascoBegoña Verdejo

subject

Biomimetic materialsAza CompoundsManganeseMacrocyclic CompoundsStereochemistrySuperoxide DismutaseMetals and AlloysMolecular Conformationchemistry.chemical_elementGeneral ChemistryManganeseElectrochemistryCrystallography X-RayCatalysisMolecular conformationSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryBiomimetic MaterialsCoordination ComplexesMaterials ChemistryCeramics and CompositesQuinolinesAza Compounds

description

Mn(II) complexes of scorpiand-type azamacrocycles constituted by a tretrazapyridinophane core appended with an ethylamino tail including 2- or 4-quinoline functionalities show very appealing in vitro SOD activity. The observed behaviour is related to structural and electrochemical parameters.

10.1039/c1cc10526dhttps://pubmed.ncbi.nlm.nih.gov/21537499