6533b86dfe1ef96bd12ca0b6
RESEARCH PRODUCT
Some notes on the geographical distribution of the human red cell acid phosphatase phenotypes
H. WalterR. Ananthakrishnansubject
GeneticsTropical ClimateErythrocytesPolymorphism GeneticGeographyRed cell acid phosphataseClimateAcid PhosphataseStatistics as TopicAdaptation BiologicalZoologyBiologySignificant negative correlationPhenotypeGenetics PopulationPhenotypeGene FrequencyGeneticsHumansMetabolic diseaseNegative correlationAlleleMolecular BiologyAllelesGenetics (clinical)description
Basing on the data of 65 populations the geographical variability of the human red cell acid phosphatase phenotypes resp. alleles was studied. We found a marked distribution gradient: The frequency of pB-alleles increases with the increase of the mean annual temperature of the various biotops, whereas the pA-allele frequencies show a clear decrease. For this allele we calculated a significant negative correlation between its frequency and the mean annual temperature: r=-0.71; P<0.001. We suppose that the pB-allele is in some way adaptive under the climatic conditions of tropical biotops. The possible reasons are discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1972-01-01 | Human Genetics |