Molecular topology: a useful tool for the search of new antibacterials.

6533b86dfe1ef96bd12cab90

RESEARCH PRODUCT

Molecular topology: a useful tool for the search of new antibacterials.

M.j. Ros S. Wolski Jorge Galvez Ramón García-domenech C. De Gregorio Alapont M.d. Garcı́a

subject

chemistry.chemical_classification Neohesperidin Molecular model Bacteria medicine.drug_class Stereochemistry Organic Chemistry Clinical Biochemistry Antibiotics Flavonoid Pharmaceutical Science Mordant Biochemistry Combinatorial chemistry Anti-Bacterial Agents Hesperidin chemistry.chemical_compound chemistry Drug Discovery medicine Molecular Medicine Molecular Biology Topology (chemistry)Antibacterial agent

description

Molecular topology has been applied to find new lead antibacterial compounds. Among the selected compounds, hesperidin, neohesperidin and Mordant Brown 24 stand out, with minimum inhibitory concentrations 90, MIC90<0.3 mg / mL.

year	journal	country	edition	language
2000-09-15	Bioorganicmedicinal chemistry letters

10.1016/s0960-894x(00)00406-6 https://pubmed.ncbi.nlm.nih.gov/10987443

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