6533b86efe1ef96bd12cac58
RESEARCH PRODUCT
Clinicopathological evaluation of 164 dental follicles and dentigerous cysts with emphasis on the presence of odontogenic epithelium in the connective tissue. The hypothesis of "focal ameloblastoma"
I. Van Der WaalMarco Meletisubject
MalePathologymedicine.medical_specialtyDentigerous CystConnective tissueOdontologíaEpitheliumAmeloblastomaYoung AdultSDG 3 - Good Health and Well-beingDental SacOral and maxillofacial pathologymedicineHumansAmeloblastomaGeneral DentistryDental folliclebusiness.industryDental Sac:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludEpitheliumDentigerous cystmedicine.anatomical_structureOtorhinolaryngologyConnective TissueUNESCO::CIENCIAS MÉDICASOral and maxillofacial surgery/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleResearch-ArticleSurgeryOral Surgerybusinessdescription
Objectives: Some ameloblastomas presumably originate from odontogenic epithelium within the connective tissue of dental follicles and dentigerous cysts. Therefore, it would seem reasonable to discuss as whether odontogenic epithelium proliferations, frankly displaying ameloblastomatous features (“focal ameloblastoma”), should be considered as an “early” ameloblastoma. Study Design: Histopathological reports from 164 dental follicles and dentigerous cysts from the Department of Oral and Maxillofacial Surgery/Oral Pathology of the VU Free University medical center in Amsterdam, The Ne-therlands, were reviewed. Histopathological slides from 39 cases reporting the presence of odontogenic epithelium within the connective tissue were re-evaluated in order to assess the possible presence of focal ameloblastomas. Results: Focal ameloblastomas were detected in one dental follicle and in two dentigerous cysts. During a follow-up period of 6, 8 and 22 years, respectively, no clinical signs of (recurrent) ameloblastoma have occurred in these patients. Conclusions: Focal ameloblastoma possibly represents the early stage of ameloblastoma development. Key words:Ameloblastoma, odontogenic epithelium, dentigerous cyst, dental follicle.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-03-28 |