6533b86efe1ef96bd12cb220

RESEARCH PRODUCT

Klinisch-experimentelle Studie zur szintigraphischen Darstellung maligner Kopf-Hals-Neoplasien mit57Cobalt-Bleomycin

H JungH GammD Eissner

subject

medicine.medical_specialtyCobalt RadioisotopesOtorhinolaryngologyOtorhinolaryngologybusiness.industrymedicineHead and neck surgeryRadionuclide imagingGeneral MedicineNeurosurgeryRadiologyHead and neckbusiness

description

Tumorscanning of malignomas and their metastatic nodules in head and neck is an enrichment of diagnostic possibilities. For the examination such substances can be used, which are tumoraffine and well to mark with a radio-isotope. Therefore we have marked the cytostatic drug Bleomycine with 57Co. Scans were performed with the Anger-Camera 4 to 6 hrs after intravenous injection of 1 mCi 57Co-Bleomycine. 60 patients with different malignomas have been examined, 46 with tumor-localization in head and neck, the others in thoraxabdomen. 34 (85%) of the head and neck malignomas could be demonstrated; 21 (81%) were squamous cell carcinomas, 13 (69%) sarcomas. The possibilities of this method are shown; its clinical importance lies in the identification of primary tumors and their metastatic nodules, of relapses and tumorrests as well as the localization of distant metastasises.

https://doi.org/10.1007/bf01221120