6533b86efe1ef96bd12cb58f

RESEARCH PRODUCT

Remembering what but not where: independence of spatial and visual working memory in the human brain

Roberta PerriCarlo CaltagironeGiovanni Augusto CarlesimoPatrizia TurrizianiFrancesco Tomaiuolo

subject

Malegenetic structuresCognitive NeuroscienceShort-term memoryExperimental and Cognitive PsychologyNeuropsychological TestsSpatial memoryMagnetic Resonance Imaging; Frontal Lobe; Imagination; Humans; Brain; Space Perception; Middle Aged; Neuropsychological Tests; Parietal Lobe; Memory Disorders; Visual Perception; MaleImagery; Visuo-spatial memory; Working memory; Brain; Frontal Lobe; Humans; Imagination; Magnetic Resonance Imaging; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Parietal Lobe; Space Perception; Visual PerceptionVisual memoryParietal LobeHumansImageryVisual short-term memoryMemory DisordersSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaWorking memoryLong-term memoryWorking memoryParietal lobeBrainVisuo-spatial memoryMiddle AgedMagnetic Resonance Imagingeye diseasesNeuroanatomy of memoryFrontal LobeNeuropsychology and Physiological PsychologySpace PerceptionImaginationVisual PerceptionSettore MED/26 - NeurologiaPsychologyNeuroscience

description

We report the neuropsychological and MRI investigation of a patient (MV) who developed a selective impairment of visual-spatial working memory (WM) with preservation not only of verbal, but also of visual shape WM, following an ischemic lesion in the cerebral territory supplied by one of the terminal branches of the right anterior cerebral artery. MV was defective in visual-spatial WM whether the experimental procedure involved arm movement for target pointing or not. Also, in agreement with the role generally assigned to visual-spatial WM in visual imagery. MV was extremely slow in the mental rotation of visually and verbally presented objects. In striking contrast with the WM deficit, MV's visual-spatial long-term memory was intact. The behavioral and neuroanatomical investigation of MV provides support for the hypothesis that the superior frontal gyrus (BA 6) and the dorsomedial cortex of the parietal lobe (BA 7) are part of the neural circuitry underlying visual-spatial WM in humans. © 2001 Elsevier Masson Srl.

http://hdl.handle.net/2108/67260