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RESEARCH PRODUCT
HLA antigens in ulcerative colitis: a study in the Sicilian population
Mario CottonePatrizia PalmeriL. OlivaAmbrogio OrlandoCalogero Carusosubject
education.field_of_studybusiness.industryImmunologyPopulationGeneral MedicineHuman leukocyte antigenmedicine.diseaseBiochemistryUlcerative colitisGene FrequencyItalyAntigenHLA AntigensImmunologyGeneticsHumansImmunology and AllergyMedicineColitis Ulcerativeeducationbusinessdescription
HLA antigens were investigated in 41 Sicilian patients with ulcerative colitis and in 151 healthy controls. Frequencies of HLA-B5 and DR2 were increased in the group of patients with ulcerative colitis whereas the DR3 antigen frequency was decreased. However the corrected p values were not significant. Thus, present results indicate that in ulcerative colitis HLA linked genetic factors play a marginal role, if any.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2008-12-11 | Tissue Antigens |