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RESEARCH PRODUCT
A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
Castelli ElenaCaputo ValentinaBongiorno Maria RitaGurreri RosarioPistone GiuseppeCuriale SalvatricePardo Nicolasubject
medicine.medical_specialtybusiness.industryInterleukin-17ApocrineInterleukinCase ReportInflammationDermatologymedicine.diseaseDermatologyPathogenesisHidradenitis suppurativa030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisPsoriasismedicinePsoriasisHidradenitis suppurativaSecukinumabInterleukin 17medicine.symptombusinessdescription
Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-06-01 | Annals of Dermatology |