6533b86ffe1ef96bd12ce77d
RESEARCH PRODUCT
Asymmetric hydrogenation of ethyl pyruvate over aqueous dispersed Pt nanoparticles stabilized by a cinchonidine-functionalized β-cyclodextrin
Stéphane MenuelBastien LégerSébastien TilloyHervé BricoutIveta TicháEric MonflierSébastien NoëlJindřich JindřichAnne PonchelAlessandro GaliaEleonora Caroniasubject
Metal nanoparticles010402 general chemistryPlatinum nanoparticles01 natural sciencesCatalysisCatalysislcsh:Chemistrychemistry.chemical_compoundPolymer chemistryCyclodextrinMoiety[CHIM]Chemical SciencesCinchonidineCinchonidinechemistry.chemical_classificationAqueous solutionCyclodextrin010405 organic chemistryChemistryProcess Chemistry and TechnologyAsymmetric hydrogenationEnantioselective synthesisGeneral Chemistry[CHIM.CATA]Chemical Sciences/CatalysisSettore ING-IND/27 - Chimica Industriale E Tecnologica0104 chemical sciencesAsymmetric hydrogenationlcsh:QD1-999Metal nanoparticles Asymmetric hydrogenation Cyclodextrin Cinchonidinedescription
International audience; Cinchonidine-functionalized β-cyclodextrin was used as stabilizing agent for platinum nanoparticles dispersed in water, but also as chiral modifier for the asymmetric hydrogenation of ethyl pyruvate at 30 °C under 40 bar of hydrogen. This functionalized cyclodextrin allowed getting more stable, more catalytically active and also more enantioselective Pt nanoparticles compared to control catalytic systems. NMR and MALDI-MS analyses clearly showed the reduction of the vinyl group of the cinchonidine graft during the nanoparticles preparation. Under hydrogen pressure, the hydrogenation of the quinolinic moiety was also proven and can be responsible for the difficulties encountered during the recycling study.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-02-01 |