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RESEARCH PRODUCT
Bioactive Co(II), Ni(II), and Cu(II) Complexes Containing a Tridentate Sulfathiazole-Based (ONN) Schiff Base
Aurora ReissNicoleta CioateraCezar Ionuț SpînuMihaela RotaruAnca GanescuAurelian DobrițescuFilippo ParisiIrina DăbuleanuAlice Carla CarabetPetre Rotarusubject
Pharmaceutical ScienceOrganic chemistrythermal behaviorArticleAnalytical Chemistrychemistry.chemical_compoundSchiff baseQD241-441sulfathiazoleantibacterial activityNickelDrug DiscoveryOctahedral molecular geometryMoleculePhysical and Theoretical ChemistryThiazoleSchiff BasesSulfathiazolesSchiff baseChemistryLigandSpectrum AnalysisCobaltAnti-Bacterial AgentsThermogravimetryCrystallographySalicylaldehydeChemistry (miscellaneous)Molecular MedicineCo(II) Ni(II) and Cu(II) complexesCopperMonoclinic crystal systemdescription
New Co(II), Ni(II), and Cu(II) complexes were synthesized with the Schiff base ligand obtained by the condensation of sulfathiazole with salicylaldehyde. Their characterization was performed by elemental analysis, molar conductance, spectroscopic techniques (IR, diffuse reflectance and UV–Vis–NIR), magnetic moments, thermal analysis, and calorimetry (thermogravimetry/derivative thermogravimetry/differential scanning calorimetry), while their morphological and crystal systems were explained on the basis of powder X-ray diffraction results. The IR data indicated that the Schiff base ligand is tridentate coordinated to the metallic ion with two N atoms from azomethine group and thiazole ring and one O atom from phenolic group. The composition of the complexes was found to be of the [ML2]∙nH2O (M = Co, n = 1.5 (1)
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-05-01 | Molecules |