Search results for "Sulfathiazoles"

showing 2 items of 2 documents

Nuclease activity of [Cu(sulfathiazolato)2(benzimidazole)2]2MeOH. Synthesis, properties and crystal structure

2002

The [Cu(sulfathiazolato)(2)(benzimidazole)(2)]2MeOH complex has been synthesised and characterised. It crystallises in the monoclinic system, space group C1c1, with unit cell dimensions a=18.829(7) A, b=12.206(3) A, c=17.233(5) A, alpha=90.06(2) degrees, beta=97.28(3) degrees, gamma=90.21(3) degrees and Z=4. The geometry around the copper(II) ion is intermediate between tetrahedral and square planar. The complex produces cleavage of plasmid pUC18 in presence of reducing agents. The efficiency of cleavage reaction of the title compound with pUC18 and with different reducing agents follows the order ascorbate-H(2)O(2)>ascorbate>MPA>dithiothreitol>H(2)O(2).

Models MolecularBenzimidazoleSpectrophotometry InfraredReducing agentMolecular Conformationchemistry.chemical_elementCrystal structureCrystallography X-RayCleavage (embryo)BiochemistryDithiothreitolInorganic ChemistryStructure-Activity Relationshipchemistry.chemical_compoundSulfathiazoleOrganometallic CompoundsGroup 2 organometallic chemistrySulfathiazolesDeoxyribonucleasesMethanolElectron Spin Resonance SpectroscopyCopperCrystallographychemistryBenzimidazolesCopperPlasmidsMonoclinic crystal systemJournal of Inorganic Biochemistry
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Bioactive Co(II), Ni(II), and Cu(II) Complexes Containing a Tridentate Sulfathiazole-Based (ONN) Schiff Base

2021

New Co(II), Ni(II), and Cu(II) complexes were synthesized with the Schiff base ligand obtained by the condensation of sulfathiazole with salicylaldehyde. Their characterization was performed by elemental analysis, molar conductance, spectroscopic techniques (IR, diffuse reflectance and UV–Vis–NIR), magnetic moments, thermal analysis, and calorimetry (thermogravimetry/derivative thermogravimetry/differential scanning calorimetry), while their morphological and crystal systems were explained on the basis of powder X-ray diffraction results. The IR data indicated that the Schiff base ligand is tridentate coordinated to the metallic ion with two N atoms from azomethine group and thiazole ring a…

Pharmaceutical ScienceOrganic chemistrythermal behaviorArticleAnalytical Chemistrychemistry.chemical_compoundSchiff baseQD241-441sulfathiazoleantibacterial activityNickelDrug DiscoveryOctahedral molecular geometryMoleculePhysical and Theoretical ChemistryThiazoleSchiff BasesSulfathiazolesSchiff baseChemistryLigandSpectrum AnalysisCobaltAnti-Bacterial AgentsThermogravimetryCrystallographySalicylaldehydeChemistry (miscellaneous)Molecular MedicineCo(II) Ni(II) and Cu(II) complexesCopperMonoclinic crystal systemMolecules
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