6533b871fe1ef96bd12d0dfa

RESEARCH PRODUCT

Dialkylimidazolium dimethyl phosphates as solvents and catalysts for the Knoevenagel condensation reaction

Andris ZicmanisLiene Anteina

subject

Organic ChemistryPotentiometric titrationCondensation reactionBiochemistryCatalysisIonBenzaldehydechemistry.chemical_compoundchemistryYield (chemistry)Drug DiscoveryIonic liquidOrganic chemistryKnoevenagel condensation

description

Abstract The reaction between benzaldehyde and ethyl cyanoacetate is investigated in 1,3-dialkylimidazolium salts as solvents. The impact of both ions in these ionic liquids on the yield of the condensation reaction product is examined. Potentiometric titrations are employed for quantitative analyses of the best ionic liquids, revealing these to be 1,3-dialkylimidazolium dimethyl phosphates.

https://doi.org/10.1016/j.tetlet.2014.02.035