6533b871fe1ef96bd12d0f1a

RESEARCH PRODUCT

Novel chromosome copy number changes to predict clinical response to sunitinib in patients with advanced renal cell carcinoma

Andreas HoetkerOguz AkinAna M. MolinaChung-han LeeRobert J. MotzerJane HouldsworthSujata PatilTheresa Margaret GoldBanumathy Gowrishankar

subject

Cancer ResearchSunitinibbusiness.industryChromosomeDiseaseurologic and male genital diseasesmedicine.diseaseClear cell renal cell carcinomaOncologyRenal cell carcinomamedicineCancer researchIn patientbusinessmedicine.drug

description

4552 Background: Sunitinib is a 1st-line therapy for clear cell Renal Cell Carcinoma (ccRCC); however, 20-30% of tumors show primary resistant disease (PRD) with progression as the best response. T...

https://synapse.mskcc.org/synapse/works/80489